A Novel Method for Detection of Cancer Cell Surface

A Novel Method for Detection of Cancer Cell Surface

 

6

There are many methods for detection of biomolecular targets in the field of life science. In this work, magnetic nanoparticles were prepared by coprecipitation and modified with RGD-4C by Bao et al, and the resultant RCG-functionalized magnetic nanoparticles were used for targeting cancer cells cultured on the NiFe- based magnetic biosensing chip and distinguish the amount of cell surface receptor-integrin. Compared with traditional method, this novel method is sensitivity and specificity, large scale, high speed, low cost and minimum human intervention. It serves a good alternative with the potentials of large-scale, robustness and repeated usage, so it is promising to be used for fast diagnosis, especially for fast screening test between patients’ samples and standard controls.

Original article citation

Chenchen Bao, Lei Chen, Tao Wang, Chong Lei, Furong Tian, Daxiang Cui, Yong Zhou,“One step quick detection of cancer cell surface marker by intergrated NiFe-based magnetic biosensing cell cultural chip”, Nano-Micro Lett. 5(3), 213-222(2013). http://dx.doi.org/10.1007/BF03353752

A Highlight from Yan-Lei Liu for NMSTR.

 

Tags: 

Leave a Reply

Your email address will not be published. Required fields are marked *

*
*


*